1. From the Research Center, Hôpital Sainte-Justine, Department of Pediatrics and Pharmacology, Université de Montréal (D.L., A.M.N., X.H., S.B., M.B., F.G., I.L., S.C.), and Department of Pharmacology and Therapeutics, McGill University (D.R.V., S.C.), Montreal, Canada.