The Urinary Output of Catechol Derivatives Including Adrenaline in Normal Individuals, in Essential Hypertension, and in Myocardial Infarction

Abstract

Based on Shaw's specific test, the adrenaline content of the urine of some normal individuals was considerably higher than has been reported by those using the von Euler technic (adsorption at an alkaline pH, elution and bioassay). One patient with myocardial infarction showed highly significant amounts on four occasions. The marked elevation in the Kroneberg-Schümann catechol ratio for hypertension patients as compared with normals, reported by these authors, was not confirmed by our findings. In three cases of myocardial infarction the ratio was elevated. Our ratios for normals confirm the original work.