Affiliation:
1. Department of Radiological Sciences, UCLA School of Medicine 90024.
Abstract
Positron emission tomography offers the possibility of evaluating and quantifying regional myocardial blood flow and metabolism. Used in patients with coronary artery disease, positron emission tomography has demonstrated sustained metabolic activity in regions with reduced blood flow and impaired contractile function, and it thereby enables differentiation between viable myocardium and myocardium that has succumbed to necrosis and scar formation. Viable myocardial regions identified by metabolic rather than functional or blood-flow criteria are frequently observed in patients after an acute coronary event and in patients with stable coronary artery disease. Positron emission tomography reflects either acute myocardial ischemia, "hibernation," as well as "myocardial stunning." Findings from metabolic imaging have proved useful in characterizing more accurately coronary artery disease and its functional consequences. These findings have been found equally useful for clinical management.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference46 articles.
1. Schelbert HR Schwaiger M: PET studies of the heart in Phelps M Mazziotta J Schelbert H (eds): Positron Emission Tomography and Autoradiography: Principles and Applications for the Brain and Heart. New York Raven Press 1986 pp 581-661
2. Positron emission tomography of the heart
3. Regional myocardial perfusion assessed with N-13 labeled ammonia and positron emission computerized axial tomography
4. N-13 ammonia as an indicator of myocardial blood flow.
5. Identification and differentiation of resting myocardial ischemia and infarction in man with positron computed tomography '8F-labeled fluorodeoxyglucose and N-13 ammonia;Marshall RC;Circulation,1981
Cited by
111 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献