1. From the Department of Internal Medicine, University of Texas Medical School at Houston (S.N.H., D.-c.G., R.H., V.T.T., D.M.); the Department of Pediatrics, University of Iowa, Iowa City (M.C.W., A.M.); Human Genome Sequencing Center, Baylor College of Medicine, Houston, Tex (S.E.S.); and the Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, Tex (S.S.S.).