1. From the Division of Cardiovascular Diseases and Internal Medicine (D.M.-Z., D.D., A.J.T., M.E.-S.), Department of Pathology (M.C.-A.), Department of Radiology (P.F.S., J.F.B.), Division of Hypertension (S.T.T.), and Section of Biostatistics (C.S.), Mayo Clinic and Mayo Foundation, Rochester, Minn, and the Department of Epidemiology (L.F.B., P.A.P.), University of Michigan, Ann Arbor, Mich.