1. From the Department of Molecular Medicine, A.I. Virtanen Institute, Kuopio University, Finland (J.R., T.T.R., J.E.M., M.G., P.S., T.H., M.-R.O., S.Y.-H.); the Departments of Medicine (A.K., A.H., M.H., J.H., S.Y.-H.) and Obstetrics and Gynecology (M.-R.O.) and the Gene Therapy Unit (S.Y.-H.), Kuopio University Hospital, Kuopio, Finland; and the Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Victoria, Australia (S.A.S., M.G.A.).