Relationship between the Severity of Chest CT Scan Lesions, Arterial Oxygenation and Inflammatory Markers in High – Altitude Patients with Covid-19

Author:

Calderón-Gerstein Walter,Torres - Samaniego Gabriela,Pazos-Sovero Kevin,Calderón-Anyosa Mirella,Quisurco-Cárdenas Merly,Dorregaray-Lizárraga6 Viviana

Abstract

This study aims to determine the relationship between the severity of lung tomographic compromise with arterial oxygenation and inflammatory markers in patients with COVID-19, and to evaluate the relationship between the CTSS tomographic severity score and the mortality risk in a high-altitude population. A retrospective, longitudinal study reviewed medical records between January and July of 2021 at the Daniel Alcides Carrión Regional Teaching Clinical Surgical Hospital in Huancayo. Categorical variables were analyzed with the chi-square test, continuous variables with the ANOVA test, and correlations between continuous variables were calculated by calculating Spearman's coefficient. The predictive capacity of the CTSS score was evaluated by determining the ROC curve. Two hundred-three medical records were reviewed; 65% of patients (n = 132) were male and 84.7% came from Huancayo (n = 172). The average age was 55.86 years. 58.6% of the CT scans were in the peak phase and 14.3% in the progressive phase. The average value of the PaO2/FiO2 ratio in deceased patients was 107.4; in survivors it was 196.10. Mortality was 12% in those with mild lesions, 28.8% in those with moderate involvement, and 79.2% in those with severe pulmonary lesions. PO2/FiO2, SatO2/FiO2, DHL, CRP, D-dimer, and lymphopenia correlated with the severity of pulmonary tomographic patterns. Tomographic lesions and inflammatory marker values were more severe than in most international studies.

Publisher

LIDSEN Publishing Inc

Subject

Cell Biology,Genetics,Molecular Biology,Molecular Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3