cGAS-STING-mediated inflammation and neurodegeneration as a strategy for the treatment of neurodegenerative diseases
Author:
Publisher
China Science Publishing & Media Ltd.
Subject
General Medicine,Biochemistry,Biophysics,Molecular Biology
Link
https://engine.scichina.com/doi/pdf/310A39FECE034689A5D0048D27DC0911
Reference16 articles.
1. Gulen MF, Samson N, Keller A, Schwabenland M, Liu C, Glück S, Thacker VV. cGAS-STING drives ageing-related inflammation and neurodegeneration. Nature, 2023, 620: 374-380.
2. Szego EM, Malz L, Bernhardt N, Rösen-Wolff A, Falkenburger BH, Luksch H. Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice. eLife, 2022, 11:
3. Sharma M, Rajendrarao S, Shahani N, Ramírez-Jarquín UN, Subramaniam S. Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease. Proc Natl Acad Sci USA, 2020, 117: 15989-15999.
4. He S, Li X, Mittra N, Bhattacharjee A, Wang H, Zhao S, Liu F, et al. Microglial cGAS deletion protects against amyloid-β induced Alzheimer’s disease pathogenesis. bioRxiv 2023.
5. Udeochu JC, Amin S, Huang Y, Fan L, Torres ERS, Carling GK, Liu B. Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience. Nat Neurosci, 2023, 26: 737-750.
Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Novel Insights into Parkin–Mediated Mitochondrial Dysfunction and “Mito-Inflammation” in α-Synuclein Toxicity. The Role of the cGAS–STING Signalling Pathway;Journal of Inflammation Research;2024-07
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