FINAL VERSION PUBLISHED JUNE 16,2020 in AWWA WATER SCIENCE: https://doi.org/10.1002/aws2.1186 The coronavirus (COVID-19) pandemic prompted the closure and reopening of previously shutdown large buildings globally. Building water stagnation has been identified as a potentially serious chemical and microbiological health concern for occupants. Health officials, building owners, utilities, and other entities are rapidly developing guidance. A synthesis of peer-reviewed, government, industry, and nonprofit literature relevant to the implications of water stagnation in plumbing systems and decontamination practices for water quality and health was conducted. A primer of large building plumbing preventative and remedial strategies is provided to inform ongoing efforts to develop recommissioning guidance. Preventative practices to help avoid the need for recommissioning and specific actions, challenges, and limitations associated with recommissioning were identified and characterized. Considerations for worker and occupant safety were also indicated. The responsibility for building water safety was identified to be shared between the building owner, drinking water provider, and local and state public health authorities. [First uploaded April 7, 2020. Minor changes (funding, acknowledgments) made April 8, 2020.]