While logical deductions from data on fatalities have been unable to predict the severity of the pathological manifestations that appear in the infected, the prediction that emerged from the results obtained by illustrating the reality in which these pathological manifestations are brought about has, sadly, found confirmation in the deaths of four individuals in Brazil, Spain and India. Our topmost research priority now therefore ought to be the elucidation of the immunological conditions that give rise to immunity by means of natural infection and vaccination before this prediction is further represented in reality and graver predictions, like the catastrophic appearance of deadly outcomes of Monkeypox and Ebola without epidemiological links to Africa, are confirmed.