Fatal Methemoglobinemia Due to Industrial Accident

Abstract

This is a case of a male who fell into a vat of industrial chemicals while at work. He became unresponsive while being transported to the hospital and was pronounced dead shortly after arrival. At autopsy there was focal cyanosis, widespread first and second degree burns, chocolate-colored blood, and a postmortem methemoglobin concentration of 61.6%. An extensive search of English-language medical literature revealed that there has not been a reported case like this, in which a patient acquired methemoglobinemia by falling into a vat of industrial chemicals, was immersed in these oxidizing agents, and subsequently died. It is important when treating a victim of an accident such as this to note the chemicals to which the patient was exposed in order to understand their possible toxic effects. It is also important at autopsy to note the coloration of the blood because in this case, this is how the pathologist first suspected the possibility of methemoglobin and then ordered the appropriate diagnostic test.