Concise Review: Different Mesenchymal Stromal/Stem Cell Populations Reside in the Adult Kidney-Reference-Cited by-同舟云学术

Concise Review: Different Mesenchymal Stromal/Stem Cell Populations Reside in the Adult Kidney

Published:2014-10-29 Issue:12 Volume:3 Page:1451-1455
ISSN:2157-6564
Container-title:Stem Cells Translational Medicine
language:en
Short-container-title:

Author:

Bruno Stefania¹,Chiabotto Giulia²,Camussi Giovanni²

Affiliation:

1. Department of Molecular Biotechnology and Health Science, University of Torino, Torino, Italy

2. Department of Medical Sciences, University of Torino, Torino, Italy

Abstract

Abstract During fetal life, mesenchymal stromal/stem cells (MSCs) surround glomeruli and tubules and contribute to the development of the renal interstitium by secretion of growth factors that drive nephron differentiation. In the adult, an MSC-like population has been demonstrated in different compartments of human and murine nephrons. After injury, these cells might provide support for kidney regeneration by recapitulating the role they have in embryonic life. In this short review, we discuss the evidence of an MSC presence within the adult kidney and their potential contribution to the turnover of renal cells and injury repair.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Developmental Biology,General Medicine

Link

https://academic.oup.com/stcltm/article-pdf/3/12/1451/41892267/stcltm_3_12_1451.pdf

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