Phase II Clinical Trial of Combination Chemotherapy With Dexamethasone for Lymphoma in Dogs-Reference-Cited by-同舟云学术

Phase II Clinical Trial of Combination Chemotherapy With Dexamethasone for Lymphoma in Dogs

Published:2007-01-01 Issue:1 Volume:43 Page:27-32
ISSN:0587-2871
Container-title:Journal of the American Animal Hospital Association
language:en
Short-container-title:

Author:

Greenberg Chelsea B.¹²,Boria Pedro A.¹²,Borgatti-Jeffreys Antonella¹²,Raskin Rose E.¹²,Lucroy Michael D.¹²

Affiliation:

1. Departments of Veterinary Clinical Sciences, (Greenberg, Boria, Borgatti-Jeffreys, Lucroy) and Veterinary Pathobiology (Raskin), Purdue University, 625 Harrison Street, West Lafayette, Indiana 47907

2. From the

Abstract

Dogs with histologically confirmed lymphoma were treated with a 14-week induction chemotherapy protocol that included dexamethasone. A phase II clinical trial was done using a standard two-stage design. Complete remission occurred in 21 (88%) dogs, with a median initial progression-free interval of 186 days. Toxicity was mild and self-limiting in the majority of dogs.

Publisher

American Animal Hospital Association

Subject

Small Animals

Link

http://meridian.allenpress.com/jaaha/article-pdf/43/1/27/1330987/0430027.pdf

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