Propofol Prevents Amyloid-β-Induced Neurotoxicity through Suppression of Cytosolic Ca<sup>2＋</sup> and MAPK Signaling Pathway in SH-SY5Y Cells-Reference-Cited by-同舟云学术

Propofol Prevents Amyloid-β-Induced Neurotoxicity through Suppression of Cytosolic Ca^2＋ and MAPK Signaling Pathway in SH-SY5Y Cells

Published:2018 Issue:2 Volume:30 Page:211-226
ISSN:0915-6380
Container-title:The Showa University Journal of Medical Sciences
language:en
Short-container-title:Showa Univ J Med Sci

Author:

ONO Ran¹,OGUCHI Tatsunori¹,TSUJI Mayumi¹,OHASHI Hideaki¹,GOHMA Takumi²,SOMEI Masayuki³,INAGAKI Manami¹,KIUCHI Yuji¹

Affiliation:

1. Department of Pharmacology, Showa University School of Medicine

2. Showa University School of Pharmacy

3. Department of Anesthesiology, Showa University Koto Toyosu Hospital

Publisher

The Showa University Society

Link

https://www.jstage.jst.go.jp/article/sujms/30/2/30_211/_pdf

Reference30 articles.

1. 1） Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science. 2002;297:353-356.

2. 2） Bittner EA, Yue Y, Xie Z. Brief review: anesthetic neurotoxicity in the elderly, cognitive dysfunction and Alzheimer’s disease. Can J Anaesth. 2011;58:216-223.

3. 3） Eckenhoff RG, Johansson JS, Wei H, et al. Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. Anesthesiology. 2004;101:703-709.

4. 4） Zhang Y, Shao H, Dong Y, et al. Chronic treatment with anesthetic propofol attenuates beta-amyloid protein levels in brain tissues of aged mice. Transl Neurodegener（Internet）. 2014;3:8. （accessed 2014 April 1） Available from: https://doi.org/10.1186/2047-9158-3-8

5. 5） Pryor KO, Proekt A, Blackstock-B AS, et al. Administration of propofol after learning improves memory performance in human subjects via loss of competitive consolidation: evidence that propofol amnesia occurs at the induction of consolidation. Anesthesiology. 2012;117:BOC09.