Successful Treatment with Letermovir in a Heart Transplant Recipient with UL97 Mutation Ganciclovir-Resistant Cytomegalovirus Colitis and Viremia-Reference-Cited by-同舟云学术

Successful Treatment with Letermovir in a Heart Transplant Recipient with UL97 Mutation Ganciclovir-Resistant Cytomegalovirus Colitis and Viremia

Published:2023-03-31 Issue:1 Volume:64 Page:95-99
ISSN:1349-2365
Container-title:International Heart Journal
language:en
Short-container-title:Int. Heart J.

Author:

Yanase Tomonobu¹,Hatano Masaru¹,Bujo Chie¹,Tsuji Masaki¹,Ishida Junichi¹,Amiya Eisuke²,Okamoto Koh³,Ando Masahiko⁴,Shimada Shogo⁴,Kinoshita Osamu⁴,Fukushi Shuetsu⁵,Yamada Souichi⁵,Ono Minoru⁴,Komuro Issei¹

Affiliation:

1. Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo

2. Department of Therapeutic Strategy for Heart Failure, The University of Tokyo

3. Department of Infectious Diseases, Graduate School of Medicine, The University of Tokyo

4. Department of Cardiac Surgery, Graduate School of Medicine, The University of Tokyo

5. Department of Virology 1, National Institute of Infectious Diseases

Publisher

International Heart Journal (Japanese Heart Journal)

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Link

https://www.jstage.jst.go.jp/article/ihj/64/1/64_22-496/_pdf

Reference22 articles.

1. 1. Aryal S, Katugaha SB, Cochrane A, et al. Single-center experience with use of letermovir for CMV prophylaxis or treatment in thoracic organ transplant recipients. Transpl Infect Dis 2019; 21: e13166.

2. 2. Stoelben S, Arns W, Renders L, et al. Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study. Transpl Int 2014; 27: 77-86.

3. 3. Schreiber A, Härter G, Schubert A, Bunjes D, Mertens T, Michel D. Antiviral treatment of cytomegalovirus infection and resistant strains. Expert Opin Pharmacother 2009; 10: 191-209.

4. 4. Chou S. Cytomegalovirus UL97 mutations in the era of ganciclovir and maribavir. Rev Med Virol 2008; 18: 233-46.

5. 5. Goldner T, Hewlett G, Ettischer N, Ruebsamen-Schaeff H, Zimmermann H, Lischka P. The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase. J Virol 2011; 85: 10884-93.