The relationship of uric acid levels with lipid parameters and body mass index in healthy individuals

Abstract

Aim: The relationship between hypertension, dyslipidemia, atrial fibrillation, obesity, and diabetes, which are cardiovascular risk factors, and a high serum uric acid level has been reported in the literature. However, the effectiveness of the adjustments to be made in uric asid levels on these diseases has not been clearly demonstrated yet. This study focuses on the relationship between serum uric acid levels and body mass index and lipid profile of healthy individuals. Methods: Records of healthy volunteers obtained form the Family Medicine outpatient clinic were reviewed. Body mass index, serum uric acid, low-density lipoprotein, high-density lipoprotein, total cholesterol and triglyceride levels were analyzed retrospectively. Results: Data from a total of 126 participants (90 female [71.4%], 36 male [28.6%]) were examined. Serum uric acid levels were correlated with body mass index (p=0.000, r=0.571) and serum triglyceride levels (p=0.001, r=0.397). No correlation was found between serum uric acid and lipoproteins and total cholesterol. Conclusion: This study found that increased serum uric acid levels are associated with increased body mass index and increased serum triglyceride levels. Additionally, serum uric acid levels were higher in men. We recommend the routine assessment of uric acid levels during periodic health examinations.