Aptamer: A New Class of Oligonucleotide for Therapeutic and Diagnostic Use - Review

Abstract

Recently, aptamers get the attention of many scientist, because they have all advantages of antibodies which found in human body. They also have unique merits like thermal stability, low cost, and many more. Aptamers are the short sequence nucleic acid with a high affinity and specificity. It is globally adopted as a one of the advance and promising drug delivery technique. These aptamers are produced by in vitro selection method using SELEX technique. This review contains the discussion on the aspect of design, unique properties, applications of aptamers to aid in cancer diagnosis, prevention and treatment under fine condition. Finally, several medical and analytical applications are presented.