Correction of dyslipidemia with combined use of beta-sitosterol and polyprenyl phosphates in dogs with type 1 diabetes mellitus

Author:

Анников Вячеслав1,Annikov Vyacheslav2,Наровлянский Александр3,Narovlyanskiy Aleksandr4,Санин Александр3,Sanin Aleksandr4,Пронин Александр3,Pronin Aleksandr4,Кожевникова Татьяна3,Kozhevnikova Tat'yana5

Affiliation:

1. ФГБОУ ВПО «Саратовский ГАУ» им. Н.И. Вавилова

2. Saratov State Agrarian University named after N.I. Vavilov

3. Федеральное государственное бюджетное учреждение «Национальный исследовательский центр эпидемиологии и микробиологии имени Н.Ф. Гамалеи» Минздрава России

4. The Gamaleya Scientific Research Institute of Epidemiology and Microbiology

5. Gamaleya Scientific Research Institute of Epidemiology and Microbiolo

Abstract

This study considers the efficiency of use of a combined drug based on beta-sitosterol and polyprenyl phosphates in dogs with type I diabetes mellitus complicated by hyperlipidemia. It was shown that after 1 month of the therapy, there was a significant decrease of the level of cholesterol, triglycerides and glucose vs. control animals. After 2 months of the therapy, in the control group the level of cholesterol and triglycerides was at the upper limit of the norm, which can lead to an exacerbation of the disease in future.

Publisher

Publishing House Logos Press

Reference12 articles.

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2. World Health Organization. Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia. Report of a WHO/IDF Consultation, Geneva, 2007, 46 p., World Health Organization. Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia. Report of a WHO/IDF Consultation, Geneva, 2007, 46 p.

3. Ganshina I.V., Sudyina G.F., Sanina V.Yu., Kozhevnikova T.N., Pronin A.V., Narovlyansky A.N., Sukhanova S.A., Proskurina O.V., Mitrokhin N .M., Sanin A.V., Phosphorylated polyprenols are a new class of compounds with anti-inflammatory and bronchodilator activity, Infection and Immunity, 2011, Vol. 1, No. 4, pp. 355-360., Ganshina I.V., Sudyina G.F., Sanina V.Yu., Kozhevnikova T.N., Pronin A.V., Narovlyansky A.N., Sukhanova S.A., Proskurina O.V., Mitrokhin N .M., Sanin A.V., Phosphorylated polyprenols are a new class of compounds with anti-inflammatory and bronchodilator activity, Infection and Immunity, 2011, Vol. 1, No. 4, pp. 355-360.

4. Elagin R.I., Cost-effectiveness of treating hyperlipidemia in patients with diabetes mellitus, Consilium Medicum, 2001, Vol. 3, No. 2, pp. 102-103 (In russ.)., Elagin R.I., Cost-effectiveness of treating hyperlipidemia in patients with diabetes mellitus, Consilium Medicum, 2001, Vol. 3, No. 2, pp. 102-103 (In russ.).

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