Intravitreal injections in veterinary ophthalmology: literature review

Author:

Бояринов Сергей1,Boyarinov Sergey2,Варёнова Татьяна3,Varenova Tat'yana4,Шилкин Алексей5,Shilkin Aleksey6

Affiliation:

1. Инновационный Ветеринарный Центр (ИВЦ) при МВА имени К.И. Скрябина

2. Innovation Veterinary Center of Moscow Veterinary Academy named after K.I. Skryabin

3. Сеть Ветеринарных Клиник «Свой Доктор»

4. Veterinary Clinic «Svoi Doctor»

5. Центр ветеринарной офтальмологии доктора Шилкина А.Г.

6. Veterinary Ophthalmology Center of Dr. Shilkin A.G

Abstract

The treatment of pathologies of posterior segment of eye, such as chorioretinitis, uveitis, various neuroretinopathies, vitreous diseases, intraocular hemorrhage, is a rather serious problem due to the difficulties of the adequate delivery of preparations into area of pathological process. One of the most effective ways to deliver drugs to eye tissue in posterior segment are intravitreal injections. The introduction of drugs is carried out directly into vitreous body through a puncture of sclera. This article presents the indications for intravitreal injections, a detailed description of properties of numerous therapeutic agents that can be delivered through intravitreal injections, potential complications of this technique and recommendations for prevention of side effects.

Publisher

Publishing House Logos Press

Reference34 articles.

1. Avery R.L., Bakri S.J., Blumenkranz M.S., Intravitreal injection technique and monitoring: updated guidelines of an expert panel, Retina, 2014 Dec, 34 Suppl, No. 12, S1‒S18., Avery R.L., Bakri S.J., Blumenkranz M.S., Intravitreal injection technique and monitoring: updated guidelines of an expert panel, Retina, 2014 Dec, 34 Suppl, No. 12, S1‒S18.

2. Boyko E.V., Sosnovsky S.V., Berezin R.D., Kacherovich P.A., Tavtilova D.A., Intravitreal injections: theory and practice, Ophthalmological statements, 2010,Vol. III, No. 2, pp. 28‒35., Boyko E.V., Sosnovsky S.V., Berezin R.D., Kacherovich P.A., Tavtilova D.A., Intravitreal injections: theory and practice, Ophthalmological statements, 2010,Vol. III, No. 2, pp. 28‒35.

3. Brown C.A., Penicillin in ophthalmology: The bacteriological, experimental, and clinical evidence of its value, including a personal series of 125 clinical cases, Br. J. Ophthalmol., 1946, Vol. 30, No. 3, pp. 146–167., Brown C.A., Penicillin in ophthalmology: The bacteriological, experimental, and clinical evidence of its value, including a personal series of 125 clinical cases, Br. J. Ophthalmol., 1946, Vol. 30, No. 3, pp. 146–167.

4. Cardillo J.A., Farah M.E., Mitre J., An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy, Br J Ophthalmol, 2004, No. 88, pp. 1201–1205., Cardillo J.A., Farah M.E., Mitre J., An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy, Br J Ophthalmol, 2004, No. 88, pp. 1201–1205.

5. Duke F.D., Strong T.D., Bentley E., Dubielzig R.R., Feline ocular tumors following ciliary body ablation with intravitreal gentamicin, Vet Ophthalmol., 2013 Jul, 16 Suppl, No. 1, pp. 188‒190. doi: 10.1111/vop.12066. Epub 2013 May 22., Duke F.D., Strong T.D., Bentley E., Dubielzig R.R., Feline ocular tumors following ciliary body ablation with intravitreal gentamicin, Vet Ophthalmol., 2013 Jul, 16 Suppl, No. 1, pp. 188‒190. doi: 10.1111/vop.12066. Epub 2013 May 22.

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