Alpha-2adrenoreceptor agonists. Dexmedetomidine-Reference-Cited by-同舟云学术

Alpha-2adrenoreceptor agonists. Dexmedetomidine

Published:2024-05-18 Issue: Volume: Page:47-51
ISSN:2500-4379
Container-title:Russian veterinary journal
language:en
Short-container-title:

Author:

Kornyushenkov Evgeniy¹²³

Affiliation:

1. Clinic of Experimental Therapy by FBSI «N.N. Blokhin National Medical Research Center of Oncology» under the Ministry of Health of the Russian Federation

2. Veterinary clinic «Biocontrol»

3. Russian veterinary society of anesthesiologists «ANO VITAR»

Abstract

Dexmedetomidine is a selective alpha2-adrenoreceptor agonist with a powerful sedative effect and analgesic properties. High selectivity of dexmedetomidine (1620:1) makes it the optimal drug among all representatives of the alpha-2adrenoreceptor agonist class for use in relatively small animals. Dexmedetomidine is currently the most popular sedative used for premedication and sedation, as well as in multimodal analgesia in a constant-rate infusion mode in intensive care. In 2024, a domestic drug with the trade name «Dexody» of the pharmaceutical company «Apicenna» with the active substance dexmedetomidine was registered. The drug is a complete analogue of the original drug and is approved for use in veterinary medicine.

Publisher

Publishing House Logos Press

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