Alpha-2adrenoreceptor agonists. Dexmethedomidine-Reference-Cited by-同舟云学术

Alpha-2adrenoreceptor agonists. Dexmethedomidine

Published:2024-05-16 Issue:2 Volume:2024 Page:47-51
ISSN:2500-4379
Container-title:Russian veterinary journal
language:en
Short-container-title:

Author:

Kornyushenkov Evgeniy¹²³

Affiliation:

1. Clinic of Experimental Therapy by FBSI «N.N. Blokhin National Medical Research Center of Oncology» under the Ministry of Health of the Russian Federation

2. Veterinary clinic «Biocontrol»

3. Russian veterinary society of anesthesiologists «ANO VITAR»

Abstract

Dexmethedomidine is a selective alpha2-adrenoreceptor agonist with a powerful sedative effect and analgesic properties. High selectivity of dexmedetomide (1620:1) makes it the optimal drug among all representatives of the alpha-2adrenoreceptor agonist class for use in relatively small animals. Dexmedetomidine is currently the most popular sedative used for premedication and sedation, as well as in multimodal analgesia in a constant-rate infusion mode in intensive care. In 2024, a domestic drug with the trade name «Dexody» of the pharmaceutical company «Apicenna» with the active substance dexmethedomidine was registered. The drug is a complete analogue of the original drug and is approved for use in veterinary medicine.

Publisher

Publishing House Logos Press

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