Threonine in mammals: indispensability and transamination
Affiliation:
1. Special design technological bureau «Biofizpribor», St. Petersburg branch of the Federal State Unitary Enterprise «Experimental- production workshops» of Federal Biomedical Agency
Abstract
As is known, amino acid threonine is not synthesized in the vertebrates when it does not come with food and the decomposition of threonine under the action of threonine dehydratase is irreversible process. Some facts point to the presence of insignificant threonine synthesis in animals. The question arises about the possibility of biosynthesis of threonine in animals in the absence of it in food, that is, its interchangeability. Research on this issue is important for compiling the diet of animals. The article shows that the threonine cannot be synthesized by reversibility of the reaction of its decomposition as well why threonine dehydrogenase in the tissues of mammals cannot be used in threonine biosynthesis. It is concluded that some quantity of threonine is involved in transamination.
Publisher
Publishing House Logos Press
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