Model of development, prevention and treatment of oral lichen planus. Part II

Abstract

Relevance. Currently, system-wide patterns of development, progression of oral lichen planus have not been studied enough. The questions of substantiation of expedient therapeutic and prophylactic measures for this disease with characteristic risk factors have not been worked out in many respects.Purpose. Identifcation of new system-wide regularities of oral lichen planus based on the development of a model for its development, prevention and treatment.Materials and methods. The study design included: the development of a model for the development, progression, prevention and treatment of oral lichen planus; clinical dental examination of 350 patients with oral lichen planus (the diagnosis was made on the basis of clinical data and the results of fluorescent diagnostics); evaluation of the effectiveness of a set of measures, including the prescription of drugs (Imudon, Kudesan, Tenoten).Results. New system-wide regularities of lichen planus are revealed. For the frst time, the relative frequencies and intensities of transitions of various forms of lichen planus from one to another are estimated. A method is proposed for estimating the moment of saturation of the therapeutic and prophylactic effect of a complex of measures on the oral mucosa with lichen planus using fluorescent diagnostics. The temporal characteristics of this moment were determined during the performance of the therapeutic and prophylactic complex.Summary. The developed model will allow, without signifcant time and material costs, justify therapeutic and prophylactic measures that are expedient for various groups of the population in case of oral lichen planus of the oral mucosa.