Comfrey (Symphytum officinale L.) root oleaginous macerate: preparation and antimicrobial action

Abstract

Medicinal comfrey (Symphytum officinale L.) preparations have anti-inflammatory, antimicrobial and pain-relieving effects, so extracts from the roots of comfrey can be incorporated into various preparations for local effects. Clinical studies were confirmed the antimicrobial activity of the plant. But there is still a need to study the antimicrobial effect of various extracts and preparations from this plant. Research problem - what extraction method will ensure the antimicrobial effect of an oil extract of comfrey? The purpose of the study: to select the method of extracting the raw material of the roots of comfrey with oil, to determine and compare the antimicrobial effect. The maceration methods were applied to the extraction of the comfrey: classic and modified. The results showed that the method of extraction from the plant raw material and the modifications of the method have an effect on the quality and effect of the extracts. Based on the result, it can be stated that maceration at higher than room temperature reduced the antimicrobial activity of the obtained macerate.