Gri Cevher Heterotopisi Bulunan Pediatrik Hastaların Manyetik Rezonans Görüntüleme Bulguları ve Eşlik Eden Malformasyonların Değerlendirilmesi

Abstract

Objective: The aim of the present study is to classify gray matter heterotopias according to magnetic resonance imaging findings and to define the accompanying malformations. Methods: Images of all pediatric patients who were detected to have heterotopia in brain magnetic resonance imaging between January 2012 and June 2020 were retrospectively evaluated. The type, location of heterotopia, and accompanying cerebral anomalies were analyzed. Results: A total of 42 patients, 22 male, and 20 female, with a mean age of 7.80 ± 4.53 years (2-16 years) with gray matter heterotopia were included in the study. Of the patients, 33 (78.6%) had subependymal, 7 (16.7%) had subcortical, and 2 (4.7%) had band heterotopia. Twenty-four patients had epilepsy. Conclusion: The sub ependymal heterotopias were frequently located in the trigon region of the lateral ventricles. All subcortical heterotopias were in the frontal and unifocal locations. Band heterotopias were located bilaterally and subcortically in a symmetrical fashion in the cerebral hemisphere. The main accompanying anomalies were ventriculomegaly, Arnold-Chiari malformation, and corpus callosum agenesis. Considering the neurological developments of pediatric patients, it is important to identify the type of heterotopia and accompanying anomalies for patient management.