Radiation study techniques in diagnosing the causes of opisthorchiasis-induced obstructive jaundice

Author:

Klimova N. V.1ORCID,Ilkanich A. Ya.1ORCID,Darvin V. V.1ORCID,Koctrubin A. L.2ORCID,Vardanyan T. S.2ORCID,Aliev F. S.3ORCID

Affiliation:

1. Surgut State University

2. Surgut District Clinical Hospital

3. Tyumen State Medical University Ministry of Health of the Russian Federation

Abstract

Objective: to analyze the diagnostic value of radiation techniques in patients with opisthorchiasis-induced obstructive jaundice and to determine the types of bile duct (BD) changes characteristic of this disease.Subjects and methods. The investigation enrolled 103 patients with chronic opisthorchiasis complicated by obstructive jaundice. For BD visualization, the investigators used radiation diagnostic methods, such as ultrasonography (USG), magnetic resonance cholangiopancreatography (MRCP), and endoscopic retrograde cholangiopancreatography (ERCP); their efficiency was evaluated.Results. ERCP and MRCP could identify 5 types of BD architectonics in opisthorchiasis-induced obstructive jaundice. The sensitivity, specificity, and overall accuracy of MRCP in diagnosing opisthorchiasis-induced sclerotic changes were 98.1, 87.5, and 96.8%, respectively.Conclusion. Among instrumental methods for diagnosing sclerotic BD changes in prolonged opisthorchiasis invasion, it is preferable to use MRCP, which is determined by its high informative value. Five types of cholangioarchitectonics are detectable in chronic opisthorchiasis complicated by obstructive jaundice.

Publisher

Luchevaya Diagnostika

Subject

General Medicine

Reference15 articles.

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3. Sripa B, Mairiang E., Thinkhamrop B. et al. Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6. Hepatology. 2009; 50(4): 1273-81.

4. Al'perovich B. I, Brazhnikova N. A., Chaj V. F. et al. Surgical aspects of the complicated and concomitant chronic opisthorchiasis. Tomsk: TML-Press; 2010 (in Russ.).

5. Brazhnikova N. A., Chaj V. F., Merzlikin N. V. Principles of treatment of obstructive jaundice opisthorchiasis' genesis. In: Materials of the XX International Congress of the Association of surgeons-hepatologists of CIS countries. Doneck; 2013: 87-8 (in Russ.).

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