A colourful consequence: The curious case of cefdinir and iron-containing supplements interaction in pediatric otitis media treatment

Author:

Alotaibi Ghallab1ORCID,AlOmeir Othman2ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy at Dawadmi, Shaqra University, Saudi Arabia

2. Department of Clinical Pharmacy, College of Pharmacy at Dawadmi, Shaqra University, Saudi Arabia.

Abstract

Otitis media (OM) is a common infection of the middle ear that often affects young children. Cefdinir, a third-generation cephalosporin, is commonly prescribed to effectively treat OM. However, when Cefdinir is co-administering with iron-containing formulations, it can potentially result in the appearance of bloody-coloured stool. We presented a 10-month-old male infant who was admitted to the emergency after experiencing reddish-coloured stool while on Cefdinir and a multivitamin-containing iron formulation three days prior to the visit. During the physical examination, all vital signs were normal, and blood tests revealed no abnormalities. Upon consultation with a drug information specialist, it was determined that the interaction between Cefdinir and iron was the likely cause, and parents were advised to discontinue the use of the antibiotic agent.

Publisher

Author Gate Publications

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