Condition after Thrombosis of the Cavernous Sinus, Complicated by Osteomyelitis of the Upper Jaw after a Coronavirus Infection in a Patient With Type 2 Diabetes Mellitus

Abstract

One of the most global health problems today is the SARS-CoV-2 coronavirus pandemic and its numerous complications. COVID-19 was first reported in China in the city of Wuhan in December 2019. It was found that coronavirus infection leads to microvascular and macrovascular complications throughout the body. Recent data indicate a strong link between severe clinical manifestations of COVID-19 and an increased risk of thromboembolism. It is associated with several risk factors such as systemic hyperinflammation caused by coronavirus infection, hypoxia, and comorbidities. The pathophysiological mechanisms underlying coagulopathy associated with COVID-19 include diffuse damage to endothelial cells, abnormal blood flow dynamics, and uncontrolled platelet activation. Studying the situation during the COVID-19 pandemic, we can notice that patients develop various complications during or after COVID-19. This article describes a clinical case of a patient with type 2 diabetes mellitus who has developed cavernous sinus thrombosis complicated by osteomyelitis of the upper jaw after COVID-19 infection.