Orbital (Retrobulbar) Meningioma in a Simmental Cow

Author:

Reis J. L.1,Kanamura C. T.2,Machado G. M.1,França R. O.1,Borges J. R. J.1,Santos R. L.3

Affiliation:

1. Faculdade de Agronomia e Medicina Veterinária, Universidade de Brasilia, Brasilia, DF, Brazil

2. Diviso de Patologia, Instituto Adolfo Lutz, São Paulo, SP, Brazil

3. Departamento de Clinica e Cirurgia Veterinárias, Escola de Veterinária da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

Abstract

A 12-year-old Simmental cow was presented with a moderately firm irregular whitish mass of approximately 5 cm in diameter, occupying the right orbit. Microscopically, a poorly differentiated neoplasm was observed. The immunohistochemical panel included cytokeratins, vimentin, epithelial membrane antigen, Factor VIII, CD34, Mart-1, Melan A, smooth muscle actin, desmin, chromogranin, neuron-specific enolase, S-100 protein, and MIB-1. The neoplasm was negative for all of them, with the exception of vimentin and S-100 protein. Transmission electron microscopy revealed abundant desmosomes. These findings support the diagnosis of orbital (retrobulbar) meningioma.

Publisher

SAGE Publications

Subject

General Veterinary

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