Hemangiopericytoma in the Eyelid of a Horse

Author:

Serena A.,Joiner K. S.,Schumacher J.

Abstract

Hemangiopericytoma (HP) is a well-recognized neoplasm arising from vascular pericytes that has been reported only in the dog and man. In this study, we describe a 14-year-old female Arabian horse that was presented for surgical excision of a 2-cm-diameter expansile subcuticular mass in the right lower eyelid. Histologically, the mass consisted of loosely arranged interlacing streams and storiform bundles of spindle cells that often formed distinct whorls around a central capillary and bundles of collagen (Antoni A-like pattern). Immunohistochemical analysis revealed strong diffuse cytoplasmic immunoreactivity for vimentin and focal immunoreactivity for smooth muscle actin, whereas neoplastic cells did not stain for Factor VIII-related antigen, Glial fibrillary acidic protein (GFAP), or S100. On the basis of histomorphology and immunohistochemical reactivity, the present tumor was diagnosed as HP. To our knowledge, this is the first report describing a HP in a horse.

Publisher

SAGE Publications

Subject

General Veterinary

Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Perivascular wall tumour in a Friesian Horse;Pferdeheilkunde Equine Medicine;2024

2. Cytology of the Eyes and Associated Structures;Equine Hematology, Cytology, and Clinical Chemistry;2020-11-20

3. Adnexal Surgery;Equine Surgery;2019

4. Fibrosarcoma of the eyelid in two sibling Czech wolfdogs;Open Veterinary Journal;2018-05-18

5. Uveal myxoid leiomyosarcoma in a horse;Clinical Case Reports;2017-09-25

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