DYSTROPHIC CALCINOSIS CUTIS IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) – CASE REPORT

Abstract

Calcinosis cutis is a rare and morbid disorder defined by calcium deposition in the cutaneous and subcutaneous layers of the skin. When associated with immune-mediated connective tissue diseases, it is classified as dystrophic calcinosis cutis, presenting with local tissue damage and normal serum calcium metabolism. It is commonly described in systemic sclerosis and dermatomyositis but rarely in association with systemic lupus erythematosus (SLE). It usually develops in women with longstanding systemic disease and Its pathophysiological mechanism is poorly understood. Characteristically, the lesions occur on the buttocks and extremities, with hardened nodules, varying in size, which may ulcerate and release white and calcareous materials with subsequent inflammation and pain. Usually it's an incidental finding, since it is often asymptomatic. Along with a compatible clinical picture, X-rays are a useful supplementary examination. Currently, there is no effective treatment available, making its therapy a constant challenge.