PREVALENCE OF ONCOGENIC VIRUSES IN TUMORS OF THE THYROID GLAND IN THE STATE OF AMAZONAS, NORTHERN BRAZIL: PRELIMINARY FINDINGS

Author:

Do Nascimento Emily Barbosa,Da Silva Jessica Miguel Medeiros,De Souza Jhonnatan Silva,Botelho João Bosco Lopes,De Lima Luiz Carlos,De Carvalho Diego Monteiro,Martins Valquíria do Carmo Alves,Ono Lia Mizobe

Abstract

INTRODUCTION: Thyroid cancer is the most prevalent type of endocrine cancer worldwide, being necessary to investigate possible associations with oncogenic viruses. OBJECTIVE: To evaluate the presence of viral infection in thyroid tissue fragments obtained surgically in a public hospital in Amazonas, Brazil. METHODS: Observational, descriptive cross-sectional study of thyroid tumor surgical specimens examined for the presence of oncogenic viruses EBV and B19 by real-time PCR. RESULTS: Sixty samples were analyzed, of which 10 had EBV DNA and 13 B19 DNA. Pearson’ chi-square test and Fisher’s exact test for the association between viral presence and tumor histological type were not statistically significant for EBV (P-value = 0.6288) or B19 (P-value = 1.0). CONCLUSION: Partial results did not reveal a positive association between viral presence and histological type.

Publisher

South Florida Publishing LLC

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