RADIOLOGICAL PROTECTION OF PATIENT WITH LIVER METASTASIS OF STRUMA OVARII SUBMITTED TO SODIUM IODIDE THERAPY (I-131)

Author:

Dos Santos Diego Mendes,Mansano Diego Henrique da Silva,Correia Júlio Marcus Sousa,Coelho Emilly Lima

Abstract

This paper presents as main objective to discuss Radiological Protection in Iodotherapy of patients with rare Hepatic metastasis of the Struma Ovarii Cancer. This was followed up for 28 days with periodic measurements of the external dose rate of the patient submitted to therapy with I-131, carried out two meters away. During the first therapeutic session, 14 days without close contact with children of their living and work were suggested. After the first 14 days of follow-up it was found by measurements and hepatic uptake of I-131, that restrictions should be maintained for another 14 days. The patient was accompanied during the whole period of social intercourse restriction. Measurements were compared with estimated dose rates of routine treatment of papillary or follicular-type thyroid cancer. The elimination of I-131 demonstrated by the dose rate measurements was shown to adjust significantly with the curve used, with correlation coefficient R = 0.9225. In contrast, the estimated curves for activities of 100, 150 and 200 mCi present better fit with R = 0.9999. The time needed for the dose rate to decrease in the level of release of the restrictions of living together was 4 times greater than the time for patients with thyroid cancer who do not live with children younger than 5 years or pregnant women; and 2 times greater than the time for patients who live with children or pregnant women. It can be concluded that different from a thyroid cancer, in this case, when treated with I-131, one can capture and retain an amount of activity that makes it impossible to release the restrictions of living together before at least 28 days. This work also suggests that the release of living restrictions depends on the biological elimination of I-131 in the patient's body. And the physiological and social conditions of each individual.

Publisher

South Florida Publishing LLC

Reference8 articles.

1. Australian Radiation Protection and Nuclear Safety Agency. Recommendations: Discharge of Patients Undergoing Treatment with Radioactive Substances. Radiation Protection Series No. 4, Brisbane, Queensland: Queensland Legislative Assembly, 2021.

2. CHERRY, Simon R; SORENSON, James A; PHELPS, Michael E. Physics in nuclear medicine, 4. ed. Philadelphia: Elsevier Health Sciences, 2012.

3. COMISSÃO NACIONAL DE ENERGIA NUCLEAR. Norma CNEN NN 3.01: Diretrizes básicas de proteção radiológica. Rio de Janeiro, 2014.

4. Fact Sheet: Guidelines for Patients Receiving Radioiodine I-131 Treatment. Society of Nuclear Medicine and Molecular Imaging (SNMMI), 2023. Disponível em: < Fact Sheet: Guidelines for Patients Receiving Radioiodine I-131 Treatment - SNMMI >. Acesso em: 26 de jun. de 2023.

5. KHERUKA, SubhashChand et al, Do current radiation safety guidelines allow the safe release of a thyroid cancer patient after high-dose radioiodine therapy? An Indian perspective, Indian Journal of Nuclear Medicine, v. 36, n. 2, p. 148, 2021.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3