Antimigraine Effects of Awei Wu Wei Pills, A Monk’s Medicine-Reference-Cited by-同舟云学术

Antimigraine Effects of Awei Wu Wei Pills, A Monk’s Medicine

Published:2023-08-18 Issue:4 Volume:21 Page:516-523
ISSN:1540-7535
Container-title:Current Topics in Nutraceutical Research
language:en
Short-container-title:CTNR

Author:

Wang Xiaorong¹²,Hu Wenjing³,Wang Tuya⁴,Wuyun Gaowa⁵

Affiliation:

1. The First Department of Encephalopathy, Affiliated Hospital of Inner Mongolia University for Nationalities, 1742 Huolinhe Street East Section, Horqin District, Tongliao City, Inner Mongolia, China

2. National Medical University of Mongolia, Ulaanbaatar City, Mongolia

3. School of Stomatology, Inner Mongolia Medical University, Jinshan Avenue (Niuniuying Village), Jinshan Development Zone, Hohhot City, Inner Mongolia Autonomous Region, China

4. Inner Mongolia Xinggan League Shoukang Hospital, Damagou District, Keyouqian Banner, Xing’an League, Inner Mongolia, China

5. Department of Nephrology of Integrated Mongolian and Western Medicine, Affiliated Hospital of Inner Mongolia University for Nationalities, No. 1742, East Section of Huolinhe Street, Horqin District, Tongliao City, Inner Mongolia, China

Abstract

The Mongolian medicine (Awei Wu Wei pills) was evaluated as a potential treatment for Hirschsprung’s migraine in a Sprague-Dawley rat model. The results of this study showed a dose-dependent decrease in the duration of ear redness and head scratching, two behavioral attributes of migraine. The mechanism involves inhibition of the c-Jun N-terminal kinase signaling pathway, leading to decreased calcitonin gene-related peptide and nitric oxide expression and reducing vasodilation, serotonin, dopamine, and beta-endorphin concentrations following administration of Awei Wu Wei pills. In conclusion, Awei Wu Wei pills demonstrate promising antimigraine effects.

Publisher

New Century Health Publishers LLC

Subject

Nutrition and Dietetics,Medicine (miscellaneous)