Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+complex reveals a novel cofactor binding mode
Author:
Publisher
Wiley
Subject
Molecular Biology,Biochemistry
Reference18 articles.
1. On transition structures for hydride transfer step: A theoretical study of the reaction catalyzed by dihydrofolate reductase enzyme;Andres;Bioorg. Chem.,1996
2. The nicotinamide dinucleotide binding motif: A comparison of nucleotide binding proteins;Bellamacina;FASEB J.,1996
3. Unusual binding stoichiometries and cooperativity are observed during binary and ternary complex formation in the single active pore of R67 dihydrofolate reductase, a D2 symmetric protein;Bradrick;Biochemistry,1996
4. Conformation of NADP+ bound to a type II dihydrofolate reductase;Brito;Biochemistry,1991
5. Crystallography and NMR system: A new software suite for macromolecular structure determination;Brunger;Acta Crystallogr. D Biol. Crystallogr.,1998
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Pharmacophore Binding Motifs for Nicotinamide Adenine Dinucleotide Analogues Across Multiple Protein Families: A Detailed Contact-Based Analysis of the Interaction between Proteins and NAD(P) Cofactors;Journal of Medicinal Chemistry;2013-07-26
2. Further Studies on the Role of Water in R67 Dihydrofolate Reductase;BIOCHEMISTRY-US;2013
3. Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure;Acta Crystallographica Section F Structural Biology and Crystallization Communications;2011-10-25
4. R67, the Other Dihydrofolate Reductase: Rational Design of an Alternate Active Site Configuration;Biochemistry;2007-12-18
5. Crystal Structure of a Type II Dihydrofolate Reductase Catalytic Ternary Complex;Biochemistry;2007-12-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3