Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin C

Author:

Fritz-Wolf Karin,Koller Klaus-Peter,Lange Gudrun,Liesum Alexander,Sauber Klaus,Schreuder Herman,Aretz Werner,Kabsch Wolfgang

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference33 articles.

1. Methods used in the structure determination of bovine mitochondrial F-1 ATPase;Abrahams;Acta Crystallogr.,1996

2. Cloning and nucleotide sequencing of new Glutaryl 7-ACA and cephalosporin C acylase genes from Pseudomonas strain;Aramori;J. Ferment. Bioeng.,1991

3. Aretz , W. Holst , U. Koller , K.-P. 1998 Induction-free process for the recombinant preparation of glutarylamidase.

4. Enzymatische Herstellung von 7-Aminocephalosporansäure;Bayer;Dechema Jahrestagungen,1996

5. A protein catalytic framework with an N-terminal nucleophile is capable of self-activation;Brannigan;Nature,1995

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