Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors-Reference-Cited by-同舟云学术

Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors

Published:2007-12 Issue:12 Volume:16 Page:2626-2635
ISSN:0961-8368
Container-title:Protein Science
language:en
Short-container-title:Protein Sci.

Author:

Ikuta Mari,Kornienko Maria,Byrne Noel,Reid John C.,Mizuarai Shinji,Kotani Hidehito,Munshi Sanjeev K.

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference46 articles.

1. A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase;Atwell;J. Biol. Chem.,2004

2. The CCP4 suite: Programs for protein crystallography;Bailey;Acta Crystallogr. D Biol. Crystallogr.,1994

3. The specificities of protein kinase inhibitors: An update;Bain;Biochem. J.,2003

4. Divergent functional roles for p90rsk kinase domains;Bjorbaek;J. Biol. Chem.,1995

5. Crystal structures of active Src kinase domain complexes;Breitenlechner;J. Mol. Biol.,2005

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of potential RSK1 inhibitors for cancer therapy using virtual screening, molecular docking, molecular dynamics simulation, and MM/GBSA calculations;Journal of Biomolecular Structure and Dynamics;2023-12-12

2. Evaluation of Pathogenicity and Structural Alterations for the Mutations Identified in the Conserved Region of the C-Terminal Kinase Domain of Human-Ribosomal S6 Kinase 1;ACS Omega;2023-04-26

3. Novel RPS6KA3 mutations cause Coffin-Lowry syndrome in two patients and concurrent compulsive eyebrow-pulling behavior in one of them;Psychiatric Genetics;2022-09-14

4. Targeting EGFR, RSK1, RAF1, PARP2 and LIN28B for several cancer type therapies with newly synthesized pyrazole derivatives via a computational study;Journal of Biomolecular Structure and Dynamics;2022-04-20

5. Design, synthesis and anti-breast cancer evaluation of biaryl pyridine analogues as potent RSK inhibitors;Bioorganic & Medicinal Chemistry Letters;2022-03