Ternary complex structure of human hgprtase, prpp, mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding-Reference-Cited by-同舟云学术

Ternary complex structure of human hgprtase, prpp, mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding

Published:1999 Issue:5 Volume:8 Page:1023-1031
ISSN:0961-8368
Container-title:Protein Science
language:en
Short-container-title:Protein Sci.

Author:

Balendiran Ganesaratnam K.,Molina JOSÉ A.,Xu Yiming,Torres-Martinez Jan,Stevens Robert,Focia Pamela J.,Eakin Ann E.,Sacchettini James C.,Craig Sydney P.

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference39 articles.

1. Purine and Pyrimidine Metabolism

2. Kinetic mechanism of orotate phosphoribosyltransferase from Salmonella typhimurium;Bhatia;Biochemistry,1990

3. Slow-cooling protocols for crystallographic refinement by simulated annealing;Brünger;Acta Crystallogr A,1990

4. Statistical analysis of enzyme kinetic data;Cleland;Methods Enzymol,1979

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