IN SILICO DETERMINATION OF THE PROBABLE TARGETS FOR LECTINS BINDING IN MIXED FEEDS-Reference-Cited by-同舟云学术

IN SILICO DETERMINATION OF THE PROBABLE TARGETS FOR LECTINS BINDING IN MIXED FEEDS

Published:2022 Issue:1 Volume:58 Page:12-16
ISSN:2078-0109
Container-title:Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine
language:ru
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Author:

Kavalionak Y.K.¹^ORCID,Dabravolski S.A.¹^ORCID,Kavalionak N.P.¹

Affiliation:

1. Vitebsk State Academy of Veterinary Medicine

Abstract

The study of the interaction of plant lectins with the target intestinal receptors of the weaning piglets by the in silico computer modelling method showed that the most probable targets for the lectin binding are the divalent metal transporter 1 (DMT1) and neutral amino acid transporter. Barley lectins have the greatest potential for interaction. Legume-type lectins and the OS9-like protein are the main types of reactive lectins. The addition of specific carbohydrates is the optimal method for neutralization of lectins.

Publisher

Vitebsk State Academy of Veterinary Medicine

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