Affiliation:
1. All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy
Abstract
The mutagenic properties of a new combined antibacterial drug “Marbotrim” were investigated by a micronucleus test of polychromatophilic erythrocytes and by accounting technique for chromosomal aberrations in mouse bone marrow cells. The frequency of occurrence of cells with chromosomal aberrations and polychromatophilic erythrocytes with micronuclei in the study groups did not have statistically significant differences compared to the values of the negative control group. The presented data can be evidence of the absence of the effect of Marbotrim on the genetic stability of animal cells.
Publisher
Vitebsk State Academy of Veterinary Medicine