LEVEL OF CD-3 LYMPHOCYTES IN THE MUCOSA OF THE SMALL INTESTINE OF PIGLETS IN A COMPLEX THERAPY OF GASTROINTESTINAL DISEASES OF BACTERIAL ETIOLOGY-Reference-Cited by-同舟云学术

LEVEL OF CD-3 LYMPHOCYTES IN THE MUCOSA OF THE SMALL INTESTINE OF PIGLETS IN A COMPLEX THERAPY OF GASTROINTESTINAL DISEASES OF BACTERIAL ETIOLOGY

Published:2021 Issue:3 Volume:57 Page:8-12
ISSN:2078-0109
Container-title:Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine
language:ru
Short-container-title:

Author:

Vorotnikova S.M.¹^ORCID,Shabunin B.V.¹^ORCID,Mikhailov E.V.¹^ORCID,Stepanov D.S.¹^ORCID

Affiliation:

1. All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy

Abstract

For the experiment, 3 groups of 40 sick piglets at the age of 5-7 days were selected, in which gastrointestinal tract diseases of mixed bacterial etiology were recorded. The first group was the control one and underwent no treatment. The animals of group 2 were administered intramuscularly the drug "Quinokol". The animals of the third group were administered “Quinokol” in combination with GM-CSF. In the immunе histochemical studies the revealed level of CD-3 positive cells in the mucous membrane in group 3 was found higher than in groups 1 and 2 by 62% and 51%, respectively. This indicates the stimulation of the migration of T cells into the intestine to maintain local immunity.

Publisher

Vitebsk State Academy of Veterinary Medicine

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