RISK FACTORS AND COMORBIDITY IN PATIENTS WITH ATRIAL FIBRILLATION AND ISCHEMIC HEART DISEASE

Abstract

The aim of the study was to evaluate the risk factors and the incidence of comorbidity in patients with coronary heart disease, depending on the presence of atrial fibrillation. Materials and methods of research: a retrospective analysis of 222 stories of illnesses of patients with coronary heart disease who undergo inpatient treatment, aged from 39 to 88 years, has been conducted. Depending on the presence of atrial fibrillation, all patients were divided into 2 groups: group 1 (main) - patients with ischemic heart disease with atrial fibrillation (n = 105), group 2 (comparison) - patients with ischemic heart disease without atrial fibrillation (n = 117). Results. In the group of patients without AF, the proportion of persons with inherited exacerbations of IHD was 64.29 %, while in the main group - 25.0 %, the differences did not reach the statistically significant level, but this relationship is confirmed by the results of the rank correlation analysis - between the presence AP and heredity revealed a significant weak feedback - c=-0.21 (p<0.05). The diseases that were observed in the examined patients with coronary artery disease present acute violation of cerebral circulation, angina pectoris, acute myocardial infarction, hypertension, diabetes, pathology of the kidneys and the thyroid gland, diastolic dysfunction and obesity. The groups differed in the proportion of patients with stroke - in the group with AF, it was significantly (p=0.002) higher - 23.81 %, in compare to 8.55 % in the comparison group. Conclusions: The presence of atrial fibrillation in patients with coronary heart disease is associated with a high degree of comorbidity. First of all, with the combination of IHD and atrial fibrillation, a high incidence of hypertension, diabetes mellitus, obesity, acute cerebrovascular disorder, kidney disease and thyroid gland is established.