The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells-Reference-Cited by-同舟云学术

The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells

Published:2021-10-01 Issue:20 Volume:32 Page:br1
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Bhagawati Maniraj¹²³,Arroum Tasnim¹,Webeling Niklas¹,Montoro Ayelén González³⁴,Mootz Henning D.²,Busch Karin B.¹

Affiliation:

1. Department of Biology, Institute of Molecular Cell Biology, and

2. Department of Chemistry and Pharmacy, Institute of Biochemistry, University of Münster, 48149 Münster, Germany

3. Center of Cellular Nanoanalytics Osnabrück, 49076 Osnabrueck, Germany

4. Cellular Communication Laboratory, Department of Biology and Chemistry, University of Osnabrueck, 49076 Osnabrueck, Germany

Abstract

The receptor Tom20 of the mitochondrial TOM complex is dynamically associated with the general import pore GIP. Single molecule tracking analysis identifies at least two subpopulations of Tom20. One Tom20 fraction is part of the trimeric TOM complex; the other is a freely diffusive Tom20 subpopulation, likely associated with VDAC.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference38 articles.

1. Respiratory Active Mitochondrial Supercomplexes

2. The Tom Core Complex

3. Single Molecule Tracking and Localization of Mitochondrial Protein Complexes in Live Cells

4. Nanoscale Organization of Mitochondrial Microcompartments Revealed by Combining Tracking and Localization Microscopy

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