Functions for Cdc42p BEM adaptors in regulating a differentiation-type MAP kinase pathway-Reference-Cited by-同舟云学术

Functions for Cdc42p BEM adaptors in regulating a differentiation-type MAP kinase pathway

Published:2020-03-15 Issue:6 Volume:31 Page:491-510
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Basu Sukanya¹,González Beatriz¹,Li Boyang¹,Kimble Garrett¹,Kozminski Keith G.²,Cullen Paul J.¹

Affiliation:

1. Department of Biological Sciences, University at Buffalo, Buffalo, NY 14260

2. Departments of Biology and Cell Biology, University of Virginia, Charlottesville, VA 22904

Abstract

How Rho GTPases are directed to effector pathways is an important question. We show here that BEM-type adaptors play unique roles in sequentially directing Cdc42 to an effector MAPK pathway. Our study may provide insight into Rho GTPase specification in other systems.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference165 articles.

1. Comparative Analysis of Transmembrane Regulators of the Filamentous Growth Mitogen-Activated Protein Kinase Pathway Uncovers Functional and Regulatory Differences

2. Metabolic Respiration Induces AMPK- and Ire1p-Dependent Activation of the p38-Type HOG MAPK Pathway

3. Role of the Unfolded Protein Response in Regulating the Mucin-Dependent Filamentous-Growth Mitogen-Activated Protein Kinase Pathway

4. The PX Domain as a Novel Phosphoinositide- Binding Module

5. Pheromone-Induced Morphogenesis Improves Osmoadaptation Capacity by Activating the HOG MAPK Pathway

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