Identification of defined structural elements within TOR2 kinase required for TOR complex 2 assembly and function in <i>Saccharomyces cerevisiae</i>-Reference-Cited by-同舟云学术

Identification of defined structural elements within TOR2 kinase required for TOR complex 2 assembly and function in Saccharomyces cerevisiae

Published:2022-05-01 Issue:5 Volume:33 Page:
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Tsverov Jennifer¹,Yegorov Kristina¹,Powers Ted¹

Affiliation:

1. Department of Molecular and Cellular Biology, College of Biological Sciences, University of California, Davis, Davis, CA 95616

Abstract

Two TOR kinase paralogues, TOR1 and TOR2, assemble preferentially into two complexes, TORC1 and TORC2. Chimeric TOR genes were constructed as a “sensitized” system for probing the importance of quaternary interactions in TORC2. This approach should be generally applicable to the study of paralogues in other systems.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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