Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast-Reference-Cited by-同舟云学术

Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

Published:2022-04-01 Issue:4 Volume:33 Page:
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Kang Pil Jung¹,Mullner Rachel¹,Li Haoyu²,Hansford Derek³,Shen Han-Wei²,Park Hay-Oak¹

Affiliation:

1. Department of Molecular Genetics, The Ohio State University, Columbus, OH 43210

2. Department of Computer Science and Engineering, The Ohio State University, Columbus, OH 43210

3. Department of Biomedical Engineering, The Ohio State University, Columbus, OH 43210

Abstract

Cdc42 is a central regulator of cell polarity in diverse cell types. Genetic analyses and live-cell imaging suggest that up-regulation of Cdc42 is likely to limit the replicative life span of budding yeast.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference51 articles.

1. On the spontaneous emergence of cell polarity

2. Some Aspects of Cell Division in Saccharomyces cerevisiae

3. Cell Polarization and Cytokinesis in Budding Yeast

4. A guided tour into subcellular colocalization analysis in light microscopy

5. Microfluidic technologies for yeast replicative lifespan studies

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