Affiliation:
1. Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS 39216-4505
Abstract
We show that coilin, the Cajal body marker protein, impacts microRNA biogenesis in cell lines with or without Cajal bodies. We also show that coilin reduction decreases DGCR8 stability and phosphorylation at S377. Collectively, our results implicate coilin as a member of the regulatory network governing miRNA biogenesis.
Publisher
American Society for Cell Biology (ASCB)
Subject
Cell Biology,Molecular Biology
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献