Quantitative biophysical metrics for rapid evaluation of ovarian cancer metastatic potential-Reference-Cited by-同舟云学术

Quantitative biophysical metrics for rapid evaluation of ovarian cancer metastatic potential

Published:2022-05-15 Issue:6 Volume:33 Page:
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Mukherjee Apratim¹,Zhang Haonan¹,Ladner Katherine²,Brown Megan³,Urbanski Jacob¹,Grieco Joseph P.³,Kapania Rakesh K.⁴,Lou Emil²,Behkam Bahareh¹,Schmelz Eva M.³,Nain Amrinder S.¹

Affiliation:

1. Department of Mechanical Engineering, Virginia Tech, Blacksburg, VA 24060

2. Division of Hematology, Oncology and Transplantation, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455

3. Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24060

4. Department of Aerospace and Ocean Engineering, Virginia Tech, Blacksburg, VA 24060

Abstract

Peritoneal cancer characterized by localized dissemination can be hard to treat due to a poor understanding of cellular properties driving metastasis. Using natural fibrillar environments, we present high throughput and high content quantitative strategy to measure biophysical properties of cells in ovarian cancer models on the timescale of hours.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

Reference85 articles.

1. Role of Collagen Fiber Morphology on Ovarian Cancer Cell Migration Using Image-Based Models of the Extracellular Matrix

2. Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

3. Metabolic changes during ovarian cancer progression as targets for sphingosine treatment

4. Mesenchymal Chemotaxis Requires Selective Inactivation of Myosin II at the Leading Edge via a Noncanonical PLCγ/PKCα Pathway

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Experimental and theoretical model for the origin of coiling of cellular protrusions around fibers;Nature Communications;2023-09-12

2. Actin Filaments Couple the Protrusive Tips to the Nucleus through the I‐BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers;Advanced Science;2023-01-25

3. Biophysics of cellular membrane shaping on fiber networks;Plasma Membrane Shaping;2023

4. Actin filaments couple the protrusive tips to the nucleus through the I-BAR domain protein IRSp53 for migration of elongated cells on 1D fibers;2022-05-20