Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport

Author:

Ramonett Aaron1,Kwak Eun-A1,Ahmed Tasmia2,Flores Paola Cruz2,Ortiz Hannah R.1,Lee Yeon Sun1,Vanderah Todd W.1,Largent-Milnes Tally1,Kashatus David F.3,Langlais Paul R.4,Mythreye Karthikeyan5,Lee Nam Y.126

Affiliation:

1. Department of Pharmacology, University of Arizona, Tucson, AZ 85724

2. Department of Chemistry & Biochemistry, University of Arizona, Tucson, AZ 85724

3. Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908

4. Department of Medicine, University of Arizona, Tucson, AZ 85724

5. Department of Pathology, University of Alabama at Birmingham, 35294

6. Cancer Center, University of Arizona, Tucson, AZ 85724

Abstract

Proper regulation of mitochondrial dynamics requires dynamin-related protein 1 retrograde movement via GAIP/RGS19-interacting protein-myosin VI transport system.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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