Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2-Reference-Cited by-同舟云学术

Phosphorylation of multiple proteins involved in ciliogenesis by Tau Tubulin kinase 2

Published:2020-05-01 Issue:10 Volume:31 Page:1032-1046
ISSN:1059-1524
Container-title:Molecular Biology of the Cell
language:en
Short-container-title:MBoC

Author:

Bernatik Ondrej¹,Pejskova Petra¹,Vyslouzil David¹,Hanakova Katerina²³,Zdrahal Zbynek²³,Cajanek Lukas¹

Affiliation:

1. Department of Histology and Embryology, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic

2. Central European Institute of Technology, Masaryk University, 62500 Brno, Czech Republic

3. National Centre for Biomolecular Research, Faculty of Science, Masaryk University, 62500 Brno, Czech Republic

Abstract

Our findings expand current knowledge of TTBK2 substrates and provide insight into extent of TTBK2-mediated phosphorylations in the context of basal body proteins and PC initiation. We further show that phosphorylation of CEP164 N-term by TTBK2 regulates ciliogenesis.

Publisher

American Society for Cell Biology (ASCB)

Subject

Cell Biology,Molecular Biology

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